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Megadeth’s Dave Mustaine Opens Up About His Painful Hand Condition And Ongoing Battle With It

Dave Mustaine has offered a starkly honest explanation regarding the physical limitations that forced his hand—quite literally.

Dave Mustaine Interview 2025

As Megadeth prepares to unleash their final studio album and embark on a massive farewell trek in 2026, frontman Dave Mustaine has offered a starkly honest explanation regarding the physical limitations that forced his hand—quite literally. In a new interview with Spain’s “MariskalRockTV,” the thrash metal architect revealed that he is suffering from Dupuytren’s contracture, a condition that is slowly compromising his ability to play the guitar.

While the decision to retire the band seemed sudden to some, Mustaine explained that it wasn’t a premeditated “announcement,” but rather a realization born out of pain during the recording sessions for the band’s upcoming self-titled LP.

“No. No, ’cause I just brought it up. I didn’t decide,” Mustaine told (as transcribed by Blabbermouth) when asked if he recalled the specific moment he chose to end his career. “We were working in the studio [on Megadeth‘s upcoming self-titled album], and it just had been a really difficult few weeks. We were trying to get everything done, and it obviously was important to us to make sure that the record was done right. And we had a bunch of deadlines we ran up against that was making it hard and stuff like that. And my hands were hurting really bad. And then I just said one day to my management, ‘You know, I don’t know how much longer I’m gonna be able to do this.’ I didn’t say, ‘Hey, I wanna retire right now.'”

The 64-year-old musician went on to give a visual demonstration of the ailment, which causes the tissue beneath the skin of the palm to thicken and tighten, eventually pulling fingers inward. Combined with severe arthritis, the condition has turned playing his intricate riffs into a daily battle.

“Yeah, you can look right here on this hand. There’s a line right there that’s sticking up. That’s something called Dupuytren’s contracture, and it’s gonna make my finger come down like this. It’s already started, where it’s kind of bunching up a little bit,” Mustaine revealed. “And then if you look at the tips of my fingers, they’re severely arthritic. So, all those bumps makes it really painful to play.”

Despite the pain, Mustaine is wary of surgical intervention. He explained that the risk of a botched procedure is too high while he still has a final tour to complete. He would rather play through the pain at near-full capacity than risk a surgery that could permanently sideline him before he has the chance to say goodbye to his fans properly.

“I’m gonna wait for that until I’m ready to try it, because if I try it now and I’m 95 percent, and I do a surgery and it sets me back, that would’ve been a bad decision,” he reasoned. “If I wait until my hands are causing a problem and I try it and it doesn’t work, well then I’ve toured everywhere, I’ve said farewell to everybody and I’m not leaving stuff unsaid or unfinished.”

These physical struggles are the driving force behind the upcoming “This Was Our Life” tour, which kicks off in 2026. Speaking earlier this month to SiriusXM‘s “Trunk Nation With Eddie Trunk,” Mustaine admitted that his body—specifically his hands and his spine—was “letting him down,” prompting the need to wind down operations while the band can still deliver a top-tier performance.

The band’s final album, simply titled Megadeth, is slated for release in January.

Written By

Ogorthul: Immersed in the bone-shattering world of death metal and beyond. I'm here to excavate the latest news, reviews, and interviews from the extreme metal scene for you.

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